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3-Amino-N-benzyl-6-(4-fluoro­phen­yl)thieno[2,3-b]pyridine-2-carboxamide

In the title compound, C(21)H(16)FN(3)OS, the thieno[2,3-b]pyridine system forms dihedral angles of 10.57 (12) and 83.87 (5)° with the fluoro­phenyl ring at the 6-position and the phenyl ring of the benzyl group, respectively. In the crystal, mol­ecules are linked by weak N—H⋯N anf N—H⋯O hydrogen bo...

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Detalles Bibliográficos
Autores principales: Zhao, Jin-Ni, Yang, Sheng-Yong, Yang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379397/
https://www.ncbi.nlm.nih.gov/pubmed/22719595
http://dx.doi.org/10.1107/S160053681202212X
Descripción
Sumario:In the title compound, C(21)H(16)FN(3)OS, the thieno[2,3-b]pyridine system forms dihedral angles of 10.57 (12) and 83.87 (5)° with the fluoro­phenyl ring at the 6-position and the phenyl ring of the benzyl group, respectively. In the crystal, mol­ecules are linked by weak N—H⋯N anf N—H⋯O hydrogen bonds and π–π stacking inter­actions involving fluoro­phenyl rings of adjacent mol­ecules, with a centroid–centroid distance of 3.648 (10) Å. In addition, intra­molecular N—H⋯S and N—H⋯O hydrogen bonds contribute to the stability of the mol­ecular conformation.