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N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide
The title compound, C(10)H(5)ClF(2)N(2)OS, was obtained by linking an amino heterocycle and a substituted benzoyl chloride. The dihedral angle between the two rings is 41.2 (2)° and the equalization of the amide C—N bond lengths reveals the existence of conjugation between the benzene ring and the t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
International Union of Crystallography
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379424/ https://www.ncbi.nlm.nih.gov/pubmed/22719622 http://dx.doi.org/10.1107/S1600536812022477 |
| _version_ | 1782236196805541888 |
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| author | Liu, Xi-Wang Li, Jian-Yong Zhang, Han Yang, Ya-Jun Zhang, Ji-Yu |
| author_facet | Liu, Xi-Wang Li, Jian-Yong Zhang, Han Yang, Ya-Jun Zhang, Ji-Yu |
| author_sort | Liu, Xi-Wang |
| collection | PubMed |
| description | The title compound, C(10)H(5)ClF(2)N(2)OS, was obtained by linking an amino heterocycle and a substituted benzoyl chloride. The dihedral angle between the two rings is 41.2 (2)° and the equalization of the amide C—N bond lengths reveals the existence of conjugation between the benzene ring and the thiazole unit. In the crystal, pairs of N—H⋯N hydrogen bonds link molecules into inversion dimers. Non-classical C—H⋯F and C—H⋯O hydrogen bonds stabilize the crystal structure. |
| format | Online Article Text |
| id | pubmed-3379424 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | International Union of Crystallography |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33794242012-06-20 N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide Liu, Xi-Wang Li, Jian-Yong Zhang, Han Yang, Ya-Jun Zhang, Ji-Yu Acta Crystallogr Sect E Struct Rep Online Organic Papers The title compound, C(10)H(5)ClF(2)N(2)OS, was obtained by linking an amino heterocycle and a substituted benzoyl chloride. The dihedral angle between the two rings is 41.2 (2)° and the equalization of the amide C—N bond lengths reveals the existence of conjugation between the benzene ring and the thiazole unit. In the crystal, pairs of N—H⋯N hydrogen bonds link molecules into inversion dimers. Non-classical C—H⋯F and C—H⋯O hydrogen bonds stabilize the crystal structure. International Union of Crystallography 2012-05-23 /pmc/articles/PMC3379424/ /pubmed/22719622 http://dx.doi.org/10.1107/S1600536812022477 Text en © Liu et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| spellingShingle | Organic Papers Liu, Xi-Wang Li, Jian-Yong Zhang, Han Yang, Ya-Jun Zhang, Ji-Yu N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title |
N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title_full |
N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title_fullStr |
N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title_full_unstemmed |
N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title_short |
N-(5-Chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| title_sort | n-(5-chloro-1,3-thiazol-2-yl)-2,4-difluorobenzamide |
| topic | Organic Papers |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379424/ https://www.ncbi.nlm.nih.gov/pubmed/22719622 http://dx.doi.org/10.1107/S1600536812022477 |
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