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1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione

In the title mol­ecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)...

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Autores principales: El-Brollosy, Nasser R., Dege, Necmi, Demirtaş, Güneş, Attia, Mohamed I., El-Emam, Ali A., Büyükgüngör, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379431/
https://www.ncbi.nlm.nih.gov/pubmed/22719629
http://dx.doi.org/10.1107/S1600536812022350
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author El-Brollosy, Nasser R.
Dege, Necmi
Demirtaş, Güneş
Attia, Mohamed I.
El-Emam, Ali A.
Büyükgüngör, Orhan
author_facet El-Brollosy, Nasser R.
Dege, Necmi
Demirtaş, Güneş
Attia, Mohamed I.
El-Emam, Ali A.
Büyükgüngör, Orhan
author_sort El-Brollosy, Nasser R.
collection PubMed
description In the title mol­ecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08 (4)°. In the crystal, pairs of N—H⋯O hydrogen bonds link mol­ecules into inversion dimers, and weak C—H⋯O hydrogen bonds and π–π inter­actions between the benzene rings of the quinazoline ring systems [centroid–centroid distance = 3.538 (3) Å] further consolidate the packing.
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spelling pubmed-33794312012-06-20 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione El-Brollosy, Nasser R. Dege, Necmi Demirtaş, Güneş Attia, Mohamed I. El-Emam, Ali A. Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title mol­ecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08 (4)°. In the crystal, pairs of N—H⋯O hydrogen bonds link mol­ecules into inversion dimers, and weak C—H⋯O hydrogen bonds and π–π inter­actions between the benzene rings of the quinazoline ring systems [centroid–centroid distance = 3.538 (3) Å] further consolidate the packing. International Union of Crystallography 2012-05-23 /pmc/articles/PMC3379431/ /pubmed/22719629 http://dx.doi.org/10.1107/S1600536812022350 Text en © El-Brollosy et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
El-Brollosy, Nasser R.
Dege, Necmi
Demirtaş, Güneş
Attia, Mohamed I.
El-Emam, Ali A.
Büyükgüngör, Orhan
1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title_full 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title_fullStr 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title_full_unstemmed 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title_short 1-{[(2,3-Dihydro-1H-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1H,3H)-dione
title_sort 1-{[(2,3-dihydro-1h-inden-2-yl)­oxy]meth­yl}quinazoline-2,4(1h,3h)-dione
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379431/
https://www.ncbi.nlm.nih.gov/pubmed/22719629
http://dx.doi.org/10.1107/S1600536812022350
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