Cargando…
1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione
In the title molecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379431/ https://www.ncbi.nlm.nih.gov/pubmed/22719629 http://dx.doi.org/10.1107/S1600536812022350 |
_version_ | 1782236198399377408 |
---|---|
author | El-Brollosy, Nasser R. Dege, Necmi Demirtaş, Güneş Attia, Mohamed I. El-Emam, Ali A. Büyükgüngör, Orhan |
author_facet | El-Brollosy, Nasser R. Dege, Necmi Demirtaş, Güneş Attia, Mohamed I. El-Emam, Ali A. Büyükgüngör, Orhan |
author_sort | El-Brollosy, Nasser R. |
collection | PubMed |
description | In the title molecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08 (4)°. In the crystal, pairs of N—H⋯O hydrogen bonds link molecules into inversion dimers, and weak C—H⋯O hydrogen bonds and π–π interactions between the benzene rings of the quinazoline ring systems [centroid–centroid distance = 3.538 (3) Å] further consolidate the packing. |
format | Online Article Text |
id | pubmed-3379431 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | International Union of Crystallography |
record_format | MEDLINE/PubMed |
spelling | pubmed-33794312012-06-20 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione El-Brollosy, Nasser R. Dege, Necmi Demirtaş, Güneş Attia, Mohamed I. El-Emam, Ali A. Büyükgüngör, Orhan Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title molecule, C(18)H(16)N(2)O(3), the five-membered ring has an envelope conformation, with the substituted C atom deviating by 0.342 (4) Å from the mean plane P calculated for the remainder of the non-H atoms of the 2,3-dihydro-1H-indene fragment. The mean planes of quinazoline-2,4(1H,3H)-dione fragment and P form a dihedral angle of 59.08 (4)°. In the crystal, pairs of N—H⋯O hydrogen bonds link molecules into inversion dimers, and weak C—H⋯O hydrogen bonds and π–π interactions between the benzene rings of the quinazoline ring systems [centroid–centroid distance = 3.538 (3) Å] further consolidate the packing. International Union of Crystallography 2012-05-23 /pmc/articles/PMC3379431/ /pubmed/22719629 http://dx.doi.org/10.1107/S1600536812022350 Text en © El-Brollosy et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
spellingShingle | Organic Papers El-Brollosy, Nasser R. Dege, Necmi Demirtaş, Güneş Attia, Mohamed I. El-Emam, Ali A. Büyükgüngör, Orhan 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title | 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title_full | 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title_fullStr | 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title_full_unstemmed | 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title_short | 1-{[(2,3-Dihydro-1H-inden-2-yl)oxy]methyl}quinazoline-2,4(1H,3H)-dione |
title_sort | 1-{[(2,3-dihydro-1h-inden-2-yl)oxy]methyl}quinazoline-2,4(1h,3h)-dione |
topic | Organic Papers |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379431/ https://www.ncbi.nlm.nih.gov/pubmed/22719629 http://dx.doi.org/10.1107/S1600536812022350 |
work_keys_str_mv | AT elbrollosynasserr 123dihydro1hinden2yloxymethylquinazoline241h3hdione AT degenecmi 123dihydro1hinden2yloxymethylquinazoline241h3hdione AT demirtasgunes 123dihydro1hinden2yloxymethylquinazoline241h3hdione AT attiamohamedi 123dihydro1hinden2yloxymethylquinazoline241h3hdione AT elemamalia 123dihydro1hinden2yloxymethylquinazoline241h3hdione AT buyukgungororhan 123dihydro1hinden2yloxymethylquinazoline241h3hdione |