1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide

The mol­ecule of the title compound, C(12)H(15)N(3)O(2)S, which belongs to the family of thio­semicarbazones, containing an acid group, adopts a semi-closed conformation with an intramolecular N—H⋯N hydrogen bond. In the crystal, molecules are linked by strong N—H⋯O and O—H⋯S hydrogen bonds between...

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Detalles Bibliográficos
Autores principales: Mendoza-Meroño, Rafael, Menéndez-Taboada, Laura, García-Granda, Santiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379498/
https://www.ncbi.nlm.nih.gov/pubmed/22719696
http://dx.doi.org/10.1107/S1600536812023793
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author Mendoza-Meroño, Rafael
Menéndez-Taboada, Laura
García-Granda, Santiago
author_facet Mendoza-Meroño, Rafael
Menéndez-Taboada, Laura
García-Granda, Santiago
author_sort Mendoza-Meroño, Rafael
collection PubMed
description The mol­ecule of the title compound, C(12)H(15)N(3)O(2)S, which belongs to the family of thio­semicarbazones, containing an acid group, adopts a semi-closed conformation with an intramolecular N—H⋯N hydrogen bond. In the crystal, molecules are linked by strong N—H⋯O and O—H⋯S hydrogen bonds between the acid group and thiosemicarbazone unit, with one additional intermolecular hydrogen C—H⋯O interaction. These three interactions form R (2) (2)(8) and a R (2) (1)(7) rings and the molecules related by the c-glide plane are linked into a zigzag chain along [001].
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spelling pubmed-33794982012-06-20 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide Mendoza-Meroño, Rafael Menéndez-Taboada, Laura García-Granda, Santiago Acta Crystallogr Sect E Struct Rep Online Organic Papers The mol­ecule of the title compound, C(12)H(15)N(3)O(2)S, which belongs to the family of thio­semicarbazones, containing an acid group, adopts a semi-closed conformation with an intramolecular N—H⋯N hydrogen bond. In the crystal, molecules are linked by strong N—H⋯O and O—H⋯S hydrogen bonds between the acid group and thiosemicarbazone unit, with one additional intermolecular hydrogen C—H⋯O interaction. These three interactions form R (2) (2)(8) and a R (2) (1)(7) rings and the molecules related by the c-glide plane are linked into a zigzag chain along [001]. International Union of Crystallography 2012-05-31 /pmc/articles/PMC3379498/ /pubmed/22719696 http://dx.doi.org/10.1107/S1600536812023793 Text en © Mendoza-Meroño et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Mendoza-Meroño, Rafael
Menéndez-Taboada, Laura
García-Granda, Santiago
1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title_full 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title_fullStr 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title_full_unstemmed 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title_short 1-(4-Carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
title_sort 1-(4-carb­oxy­butan-2-yl­idene)-4-phenyl­thio­semicarbazide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379498/
https://www.ncbi.nlm.nih.gov/pubmed/22719696
http://dx.doi.org/10.1107/S1600536812023793
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