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Overexpression of Monocarboxylate Transporter-1 (Slc16a1) in Mouse Pancreatic β-Cells Leads to Relative Hyperinsulinism During Exercise

Exercise-induced hyperinsulinism (EIHI) is an autosomal dominant disorder characterized by inappropriate insulin secretion in response to vigorous physical exercise or pyruvate injection. Activating mutations in the monocarboxylate transporter-1 (MCT1, SLC16A1) promoter have been linked to EIHI. Exp...

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Detalles Bibliográficos
Autores principales:	Pullen, Timothy J., Sylow, Lykke, Sun, Gao, Halestrap, Andrew P., Richter, Erik A., Rutter, Guy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Islet Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379650/ https://www.ncbi.nlm.nih.gov/pubmed/22522610 http://dx.doi.org/10.2337/db11-1531

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