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Modulation of Redox Balance Leaves Murine Diabetogenic TH1 T Cells “LAG-3-ing” Behind

Preventing activation of diabetogenic T cells is critical for delaying type 1 diabetes onset. The inhibitory molecule lymphocyte activation gene 3 (LAG-3) and metalloprotease tumor necrosis factor-α converting enzyme (TACE) work together to regulate TH1 responses. The aim of this study was to determ...

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Detalles Bibliográficos
Autores principales:	Delmastro, Meghan M., Styche, Alexis J., Trucco, Massimo M., Workman, Creg J., Vignali, Dario A.A., Piganelli, Jon D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Immunology and Transplantation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379669/ https://www.ncbi.nlm.nih.gov/pubmed/22586584 http://dx.doi.org/10.2337/db11-1591

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