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CCR5 Plays a Critical Role in Obesity-Induced Adipose Tissue Inflammation and Insulin Resistance by Regulating Both Macrophage Recruitment and M1/M2 Status
C-C motif chemokine receptor (CCR)2 and its ligand, monocyte chemoattractant protein (MCP)-1, are pivotal for adipose tissue macrophage (ATM) recruitment and the development of insulin resistance. However, other chemokine systems also may play a role in these processes. In this study, we investigate...
Autores principales: | Kitade, Hironori, Sawamoto, Kazuki, Nagashimada, Mayumi, Inoue, Hiroshi, Yamamoto, Yasuhiko, Sai, Yoshimichi, Takamura, Toshinari, Yamamoto, Hiroshi, Miyamoto, Ken-ichi, Ginsberg, Henry N., Mukaida, Naofumi, Kaneko, Shuichi, Ota, Tsuguhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379680/ https://www.ncbi.nlm.nih.gov/pubmed/22474027 http://dx.doi.org/10.2337/db11-1506 |
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