Cargando…

Monounsaturated Fatty Acids Prevent the Aversive Effects of Obesity on Locomotion, Brain Activity, and Sleep Behavior

Fat and physical inactivity are the most evident factors in the pathogenesis of obesity, and fat quality seems to play a crucial role for measures of glucose homeostasis. However, the impact of dietary fat quality on brain function, behavior, and sleep is basically unknown. In this study, mice were...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sartorius, Tina, Ketterer, Caroline, Kullmann, Stephanie, Balzer, Michelle, Rotermund, Carola, Binder, Sonja, Hallschmid, Manfred, Machann, Jürgen, Schick, Fritz, Somoza, Veronika, Preissl, Hubert, Fritsche, Andreas, Häring, Hans-Ulrich, Hennige, Anita M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2012
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379681/ https://www.ncbi.nlm.nih.gov/pubmed/22492529 http://dx.doi.org/10.2337/db11-1521

Ejemplares similares

Signal Integration and Coincidence Detection in the Mitogen-activated Protein Kinase/Extracellular Signal-regulated Kinase (ERK) Cascade: CONCOMITANT ACTIVATION OF RECEPTOR TYROSINE KINASES AND OF LRP-1 LEADS TO SUSTAINED ERK PHOSPHORYLATION VIA DOWN-REGULATION OF DUAL SPECIFICITY PHOSPHATASES (DUSP1 AND -6)
por: Geetha, Nishamol, et al.
Publicado: (2011)

Cyclic GMP Kinase I Modulates Glucagon Release From Pancreatic α-Cells
por: Leiss, Veronika, et al.
Publicado: (2011)

Baseline Serum 25-Hydroxy Vitamin D Is Predictive of Future Glycemic Status and Insulin Resistance : The Medical Research Council Ely Prospective Study 1990–2000
por: Forouhi, Nita G., et al.
Publicado: (2008)

Mechanism of Oxidative DNA Damage in Diabetes : Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine-DNA Glycosylase
por: Simone, Simona, et al.
Publicado: (2008)

Integrin-Associated Protein Association With Src Homology 2 Domain Containing Tyrosine Phosphatase Substrate 1 Regulates IGF-I Signaling In Vivo
por: Maile, Laura A., et al.
Publicado: (2008)

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle
por: Morino, Katsutaro, et al.
Publicado: (2008)

Forkhead Transcription Factors (FoxOs) Promote Apoptosis of Insulin-Resistant Macrophages During Cholesterol-Induced Endoplasmic Reticulum Stress
por: Senokuchi, Takafumi, et al.
Publicado: (2008)

Human Adenovirus Type 36 Enhances Glucose Uptake in Diabetic and Nondiabetic Human Skeletal Muscle Cells Independent of Insulin Signaling
por: Wang, Zhong Q., et al.
Publicado: (2008)

Activation of Estrogen Receptor Is Crucial for Resveratrol-Stimulating Muscular Glucose Uptake via Both Insulin-Dependent and -Independent Pathways
por: Deng, Jen-Ying, et al.
Publicado: (2008)

siRNA-Mediated Reduction of Inhibitor of Nuclear Factor-κB Kinase Prevents Tumor Necrosis Factor-α–Induced Insulin Resistance in Human Skeletal Muscle
por: Austin, Reginald L., et al.
Publicado: (2008)

Autocrine IGF-1 Action in Adipocytes Controls Systemic IGF-1 Concentrations and Growth
por: Klöting, Nora, et al.
Publicado: (2008)

Metabolically Favorable Remodeling of Human Adipose Tissue by Human Adenovirus Type 36
por: Rogers, Pamela M., et al.
Publicado: (2008)

Impact of Oxidative Stress and Peroxisome Proliferator–Activated Receptor γ Coactivator-1α in Hepatic Insulin Resistance
por: Kumashiro, Naoki, et al.
Publicado: (2008)

Hypoxia Decreases Insulin Signaling Pathways in Adipocytes
por: Regazzetti, Claire, et al.
Publicado: (2009)

Dual Role of Interleukin-6 in Regulating Insulin Sensitivity in Murine Skeletal Muscle
por: Nieto-Vazquez, Iria, et al.
Publicado: (2008)

Upregulation of Mitochondrial Uncoupling Protein-2 by the AMP-Activated Protein Kinase in Endothelial Cells Attenuates Oxidative Stress in Diabetes
por: Xie, Zhonglin, et al.
Publicado: (2008)

Differential Distribution, Clustering, and Lateral Diffusion of Subtypes of the Inositol 1,4,5-Trisphosphate Receptor
por: Pantazaka, Evangelia, et al.
Publicado: (2011)

Hydrophobic Motif Phosphorylation Is Not Required for Activation Loop Phosphorylation of p70 Ribosomal Protein S6 Kinase 1 (S6K1)
por: Keshwani, Malik M., et al.
Publicado: (2011)

Submaximal Inhibition of Protein Kinase C Restores ADP-induced Dense Granule Secretion in Platelets in the Presence of Ca(2+)
por: Unsworth, Amanda J., et al.
Publicado: (2011)

Anchored Protein Kinase A Recruitment of Active Rac GTPase
por: Logue, Jeremy S., et al.
Publicado: (2011)

Klotho Depletion Contributes to Increased Inflammation in Kidney of the db/db Mouse Model of Diabetes via RelA (Serine)(536) Phosphorylation
por: Zhao, Yanhua, et al.
Publicado: (2011)

Endothelin-1 (ET-1) Increases the Expression of Remodeling Genes in Vascular Smooth Muscle through Linked Calcium and cAMP Pathways: ROLE OF A PHOSPHOLIPASE A(2)(cPLA(2))/CYCLOOXYGENASE-2 (COX-2)/PROSTACYCLIN RECEPTOR-DEPENDENT AUTOCRINE LOOP
por: Deacon, Karl, et al.
Publicado: (2010)

Cross-talk between the p38α and JNK MAPK Pathways Mediated by MAP Kinase Phosphatase-1 Determines Cellular Sensitivity to UV Radiation
por: Staples, Christopher J., et al.
Publicado: (2010)

A New Pathway of CD5 Glycoprotein-mediated T Cell Inhibition Dependent on Inhibitory Phosphorylation of Fyn Kinase
por: Bamberger, Martina, et al.
Publicado: (2011)

Identification of Human P2X1 Receptor-interacting Proteins Reveals a Role of the Cytoskeleton in Receptor Regulation
por: Lalo, Ulyana, et al.
Publicado: (2011)

Negative Regulation of TGFβ Signaling by the Kinase LKB1 and the Scaffolding Protein LIP1
por: Morén, Anita, et al.
Publicado: (2011)

Phosphatidylinositol-4-Phosphate-5-Kinase α Deficiency Alters Dynamics of Glucose-Stimulated Insulin Release to Improve Glucohomeostasis and Decrease Obesity in Mice
por: Huang, Ping, et al.
Publicado: (2011)

Cysteine Scanning Mutagenesis (Residues Glu(52)–Gly(96)) of the Human P2X1 Receptor for ATP: MAPPING AGONIST BINDING AND CHANNEL GATING
por: Allsopp, Rebecca C., et al.
Publicado: (2011)

Palmitoylation Targets AKAP79 Protein to Lipid Rafts and Promotes Its Regulation of Calcium-sensitive Adenylyl Cyclase Type 8
por: Delint-Ramirez, Ilse, et al.
Publicado: (2011)

Insulin Growth Factor-2 Binding Protein 3 (IGF2BP3) Is a Glioblastoma-specific Marker That Activates Phosphatidylinositol 3-Kinase/Mitogen-activated Protein Kinase (PI3K/MAPK) Pathways by Modulating IGF-2
por: Suvasini, Ramaswamy, et al.
Publicado: (2011)

mTORC2 Protein-mediated Protein Kinase B (Akt) Serine 473 Phosphorylation Is Not Required for Akt1 Activity in Human Platelets
por: Moore, Samantha F., et al.
Publicado: (2011)

Molecular Determinants within N Terminus of Orai3 Protein That Control Channel Activation and Gating
por: Bergsmann, Judith, et al.
Publicado: (2011)

RB1CC1 Protein Positively Regulates Transforming Growth Factor-β Signaling through the Modulation of Arkadia E3 Ubiquitin Ligase Activity
por: Koinuma, Daizo, et al.
Publicado: (2011)

Uncoupling Protein 3 (UCP3) Modulates the Activity of Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA) by Decreasing Mitochondrial ATP Production
por: De Marchi, Umberto, et al.
Publicado: (2011)

Insulin Restores Gestational Diabetes Mellitus–Reduced Adenosine Transport Involving Differential Expression of Insulin Receptor Isoforms in Human Umbilical Vein Endothelium
por: Westermeier, Francisco, et al.
Publicado: (2011)

Cross-Talk Between Interferon-γ and Hedgehog Signaling Regulates Adipogenesis
por: Todoric, Jelena, et al.
Publicado: (2011)

Dact1, a Nutritionally Regulated Preadipocyte Gene, Controls Adipogenesis by Coordinating the Wnt/β-Catenin Signaling Network
por: Lagathu, Claire, et al.
Publicado: (2009)

Protein Kinase A Regulatory Subunits in Human Adipose Tissue: Decreased R2B Expression and Activity in Adipocytes From Obese Subjects
por: Mantovani, Giovanna, et al.
Publicado: (2009)

Novel Insights into the Cellular Mechanisms of the Anti-inflammatory Effects of NF-κB Essential Modulator Binding Domain Peptides
por: Baima, Eric T., et al.
Publicado: (2010)

Regulation of Inositol 1,4,5-Trisphosphate Receptors by cAMP Independent of cAMP-dependent Protein Kinase
por: Tovey, Stephen C., et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_ihlqp8a102gsumh9jpbva8kuml