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Interaction of Caveolin-1 with Ku70 Inhibits Bax-Mediated Apoptosis
Caveolin-1, the structural protein component of caveolae, acts as a scaffolding protein that functionally regulates signaling molecules. We show that knockdown of caveolin-1 protein expression enhances chemotherapeutic drug-induced apoptosis and inhibits long-term survival of colon cancer cells. In...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380016/ https://www.ncbi.nlm.nih.gov/pubmed/22745744 http://dx.doi.org/10.1371/journal.pone.0039379 |