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Betahistine Exerts a Dose-Dependent Effect on Cochlear Stria Vascularis Blood Flow in Guinea Pigs In Vivo

OBJECTIVE: Betahistine is a histamine H(1)-receptor agonist and H(3)-receptor antagonist that is administered to treat Menière’s disease. Despite widespread use, its pharmacological mode of action has not been entirely elucidated. This study investigated the effect of betahistine on guinea pigs at d...

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Detalles Bibliográficos
Autores principales:	Ihler, Fritz, Bertlich, Mattis, Sharaf, Kariem, Strieth, Sebastian, Strupp, Michael, Canis, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380058/ https://www.ncbi.nlm.nih.gov/pubmed/22745706 http://dx.doi.org/10.1371/journal.pone.0039086

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