MicroRNA Silencing Improves the Tumor Specificity of Adenoviral Transgene Expression

Adenoviral technology has been thoroughly evaluated for delivering genetic material to tumor tissue and the surrounding microenvironment. Almost any gene can be cloned into an adenovirus (Ad) vector, which when combined with strong, constitutively active promoters permit up to a million-fold amplifi...

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Detalles Bibliográficos
Autores principales: Card, Paul B., Hogg, Richard T., del Alcazar, Carlos Gil, Gerard, Robert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380162/
https://www.ncbi.nlm.nih.gov/pubmed/22555510
http://dx.doi.org/10.1038/cgt.2012.16

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380162/
https://www.ncbi.nlm.nih.gov/pubmed/22555510
http://dx.doi.org/10.1038/cgt.2012.16

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