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MicroRNA Silencing Improves the Tumor Specificity of Adenoviral Transgene Expression
Adenoviral technology has been thoroughly evaluated for delivering genetic material to tumor tissue and the surrounding microenvironment. Almost any gene can be cloned into an adenovirus (Ad) vector, which when combined with strong, constitutively active promoters permit up to a million-fold amplifi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380162/ https://www.ncbi.nlm.nih.gov/pubmed/22555510 http://dx.doi.org/10.1038/cgt.2012.16 |