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Nedd4-2 and the Regulation of Epithelial Sodium Transport

Nedd4-2 is a ubiquitin ligase previously demonstrated to regulate endocytosis and lysosomal degradation of the epithelial Na(+) channel (ENaC) and other ion channels and transporters. Recent studies using Nedd4-2 knockout mice specifically in kidney or lung epithelia has revealed a critical role for...

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Detalles Bibliográficos
Autores principales:	Rotin, Daniela, Staub, Olivier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380336/ https://www.ncbi.nlm.nih.gov/pubmed/22737130 http://dx.doi.org/10.3389/fphys.2012.00212

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