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On the Origin of Cells and Viruses: Primordial Virus World Scenario

It is proposed that the precellular stage of biological evolution unraveled within networks of inorganic compartments that harbored a diverse mix of virus‐like genetic elements. This stage of evolution might makes up the Last Universal Cellular Ancestor (LUCA) that more appropriately could be denote...

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Autor principal: Koonin, Eugene V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Inc 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380365/
https://www.ncbi.nlm.nih.gov/pubmed/19845627
http://dx.doi.org/10.1111/j.1749-6632.2009.04992.x
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author Koonin, Eugene V.
author_facet Koonin, Eugene V.
author_sort Koonin, Eugene V.
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description It is proposed that the precellular stage of biological evolution unraveled within networks of inorganic compartments that harbored a diverse mix of virus‐like genetic elements. This stage of evolution might makes up the Last Universal Cellular Ancestor (LUCA) that more appropriately could be denoted Last Universal Cellular Ancestral State (LUCAS). Such a scenario recapitulates the ideas of J. B. S. Haldane sketched in his classic 1928 essay. However, unlike in Haldane's day, considerable support for this scenario exits today: lack of homology between core DNA replication system components in archaea and bacteria, distinct membrane chemistries and enzymes of lipid biosynthesis in archaea and bacteria, spread of several viral hallmark genes among diverse groups of viruses, and the extant archaeal and bacterial chromosomes appear to be shaped by accretion of diverse, smaller replicons. Under the viral model of precellular evolution, the key components of cells originated as components of virus‐like entities. The two surviving types of cellular life forms, archaea and bacteria, might have emerged from the LUCAS independently, along with, probably, numerous forms now extinct.
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spelling pubmed-33803652012-06-21 On the Origin of Cells and Viruses: Primordial Virus World Scenario Koonin, Eugene V. Ann N Y Acad Sci Part I. Information Processing Replaces Mechanics It is proposed that the precellular stage of biological evolution unraveled within networks of inorganic compartments that harbored a diverse mix of virus‐like genetic elements. This stage of evolution might makes up the Last Universal Cellular Ancestor (LUCA) that more appropriately could be denoted Last Universal Cellular Ancestral State (LUCAS). Such a scenario recapitulates the ideas of J. B. S. Haldane sketched in his classic 1928 essay. However, unlike in Haldane's day, considerable support for this scenario exits today: lack of homology between core DNA replication system components in archaea and bacteria, distinct membrane chemistries and enzymes of lipid biosynthesis in archaea and bacteria, spread of several viral hallmark genes among diverse groups of viruses, and the extant archaeal and bacterial chromosomes appear to be shaped by accretion of diverse, smaller replicons. Under the viral model of precellular evolution, the key components of cells originated as components of virus‐like entities. The two surviving types of cellular life forms, archaea and bacteria, might have emerged from the LUCAS independently, along with, probably, numerous forms now extinct. Blackwell Publishing Inc 2009-10-15 2009-10 /pmc/articles/PMC3380365/ /pubmed/19845627 http://dx.doi.org/10.1111/j.1749-6632.2009.04992.x Text en © 2009 New York Academy of Sciences. This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
spellingShingle Part I. Information Processing Replaces Mechanics
Koonin, Eugene V.
On the Origin of Cells and Viruses: Primordial Virus World Scenario
title On the Origin of Cells and Viruses: Primordial Virus World Scenario
title_full On the Origin of Cells and Viruses: Primordial Virus World Scenario
title_fullStr On the Origin of Cells and Viruses: Primordial Virus World Scenario
title_full_unstemmed On the Origin of Cells and Viruses: Primordial Virus World Scenario
title_short On the Origin of Cells and Viruses: Primordial Virus World Scenario
title_sort on the origin of cells and viruses: primordial virus world scenario
topic Part I. Information Processing Replaces Mechanics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380365/
https://www.ncbi.nlm.nih.gov/pubmed/19845627
http://dx.doi.org/10.1111/j.1749-6632.2009.04992.x
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