Cargando…
Aggressiveness of human melanoma xenograft models is promoted by aneuploidy-driven gene expression deregulation
Melanoma is a devastating skin cancer characterized by distinct biological subtypes. Besides frequent mutations in growth- and survival-promoting genes like BRAF and NRAS, melanomas additionally harbor complex non-random genomic alterations. Using an integrative approach, we have analysed genomic an...
Autores principales: | Mathieu, Véronique, Pirker, Christine, Schmidt, Wolfgang M., Spiegl-Kreinecker, Sabine, Lötsch, Daniela, Heffeter, Petra, Hegedus, Balazs, Grusch, Michael, Kiss, Robert, Berger, Walter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380575/ https://www.ncbi.nlm.nih.gov/pubmed/22535842 |
Ejemplares similares
-
Major vault protein supports glioblastoma survival and migration by upregulating the EGFR/PI3K signalling axis
por: Lötsch, Daniela, et al.
Publicado: (2013) -
Discrimination between 34 of 36 Possible Combinations of Three C>T SNP Genotypes in the MGMT Promoter by High Resolution Melting Analysis Coupled with Pyrosequencing Using A Single Primer Set
por: Zappe, Katja, et al.
Publicado: (2021) -
CD44 drives aggressiveness and chemoresistance of a metastatic human osteosarcoma xenograft model
por: Mayr, Lisa, et al.
Publicado: (2017) -
FGF5 is expressed in melanoma and enhances malignancy in vitro and in vivo
por: Ghassemi, Sara, et al.
Publicado: (2017) -
The deregulated microRNAome contributes to the cellular response to aneuploidy
por: Dürrbaum, Milena, et al.
Publicado: (2018)