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Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes

Epigenetic silencing by promoter methylation of genes associated with cancer initiation and progression is a hallmark of tumour cells. As a consequence, testing for DNA methylation biomarkers in plasma or other body fluids shows great promise for detection of malignancies at early stages and/or for...

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Detalles Bibliográficos
Autores principales:	Kristensen, Lasse Sommer, Raynor, Michael, Candiloro, Ida, Dobrovic, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2012
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380579/ https://www.ncbi.nlm.nih.gov/pubmed/22570110

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