Singular v Dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA Damage but opposite effects on the DNA Damage Response, Cancer Cell Growth Arrest and Apoptosis

SNF2L, an ATPase chromatin remodeling gene nearly ubiquitously expressed in diverse tissues, cancers, and derived cell lines, contributes to the chromatin remodeling complex that facilitates transcription. Because of this near ubiquitous expression, it has not been exploited as a cancer therapeutic...

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Detalles Bibliográficos
Autores principales: Ye, Yin, Xiao, Yi, Wang, Wenting, Gao, Jian-Xin, Yearsley, Kurtis, Yan, Quintao, Barsky, Sanford H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2012
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380581/
https://www.ncbi.nlm.nih.gov/pubmed/22577152

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