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Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis
Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking reti...
Autores principales: | Oehlers, Stefan H., Flores, Maria Vega, Hall, Christopher J., Crosier, Kathryn E., Crosier, Philip S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380709/ https://www.ncbi.nlm.nih.gov/pubmed/22563081 http://dx.doi.org/10.1242/dmm.009365 |
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