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Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis

Exposure to retinoids for the treatment of acne has been linked to the etiology of inflammatory bowel disease (IBD). The intestinal mucus layer is an important structural barrier that is disrupted in IBD. Retinoid-induced alteration of mucus physiology has been postulated as a mechanism linking reti...

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Detalles Bibliográficos
Autores principales: Oehlers, Stefan H., Flores, Maria Vega, Hall, Christopher J., Crosier, Kathryn E., Crosier, Philip S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380709/
https://www.ncbi.nlm.nih.gov/pubmed/22563081
http://dx.doi.org/10.1242/dmm.009365

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