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Evolutionary-inspired probabilistic search for enhancing sampling of local minima in the protein energy surface
BACKGROUND: Despite computational challenges, elucidating conformations that a protein system assumes under physiologic conditions for the purpose of biological activity is a central problem in computational structural biology. While these conformations are associated with low energies in the energy...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380728/ https://www.ncbi.nlm.nih.gov/pubmed/22759582 http://dx.doi.org/10.1186/1477-5956-10-S1-S5 |