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Identifying transcription factors and microRNAs as key regulators of pathways using Bayesian inference on known pathway structures

BACKGROUND: Transcription factors and microRNAs act in concert to regulate gene expression in eukaryotes. Numerous computational methods based on sequence information are available for the prediction of target genes of transcription factors and microRNAs. Although these methods provide a static snap...

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Detalles Bibliográficos
Autores principales: Roqueiro, Damian, Huang, Lei, Dai, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380732/
https://www.ncbi.nlm.nih.gov/pubmed/22759573
http://dx.doi.org/10.1186/1477-5956-10-S1-S15