Cargando…
Protein Scaffolds Can Enhance the Bistability of Multisite Phosphorylation Systems
The phosphorylation of a substrate at multiple sites is a common protein modification that can give rise to important structural and electrostatic changes. Scaffold proteins can enhance protein phosphorylation by facilitating an interaction between a protein kinase enzyme and its target substrate. I...
Autores principales: | Chan, Carlo, Liu, Xinfeng, Wang, Liming, Bardwell, Lee, Nie, Qing, Enciso, Germán |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380838/ https://www.ncbi.nlm.nih.gov/pubmed/22737061 http://dx.doi.org/10.1371/journal.pcbi.1002551 |
Ejemplares similares
-
Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades
por: Markevich, Nick I., et al.
Publicado: (2004) -
Effect of magnitude and variability of energy of activation in multisite ultrasensitive biochemical processes
por: Lagunes, Leonila, et al.
Publicado: (2020) -
ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1
por: Bardwell, A Jane, et al.
Publicado: (2022) -
Compact Modeling of Allosteric Multisite Proteins: Application to a Cell Size Checkpoint
por: Enciso, Germán, et al.
Publicado: (2014) -
Multisite phosphorylation code of CDK
por: Örd, Mihkel, et al.
Publicado: (2019)