Multiorgan Metastasis of Human HER-2(+) Breast Cancer in Rag2(−/−);Il2rg(−/−) Mice and Treatment with PI3K Inhibitor

In vivo studies of the metastatic process are severely hampered by the fact that most human tumor cell lines derived from highly metastatic tumors fail to consistently metastasize in immunodeficient mice like nude mice. We describe a model system based on a highly immunodeficient double knockout mou...

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Detalles Bibliográficos
Autores principales: Nanni, Patrizia, Nicoletti, Giordano, Palladini, Arianna, Croci, Stefania, Murgo, Annalisa, Ianzano, Marianna L., Grosso, Valentina, Stivani, Valeria, Antognoli, Agnese, Lamolinara, Alessia, Landuzzi, Lorena, di Tomaso, Emmanuelle, Iezzi, Manuela, De Giovanni, Carla, Lollini, Pier-Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380859/
https://www.ncbi.nlm.nih.gov/pubmed/22737248
http://dx.doi.org/10.1371/journal.pone.0039626

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