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Persistence Length of Human Cardiac α-Tropomyosin Measured by Single Molecule Direct Probe Microscopy
α-Tropomyosin (αTm) is the predominant tropomyosin isoform in adult human heart and constitutes a major component in Ca(2+)-regulated systolic contraction of cardiac muscle. We present here the first direct probe images of WT human cardiac αTm by atomic force microscopy, and quantify its mechanical...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380901/ https://www.ncbi.nlm.nih.gov/pubmed/22737252 http://dx.doi.org/10.1371/journal.pone.0039676 |