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Effect of high sugar levels on miRNA expression. Studies with galactosemic mice lenses

PURPOSE: Development of cataract is associated with apoptotic death of the lens epithelial cells. The purpose of this investigation was to examine whether this could be explained by enhancement in the expression of certain pro-apoptotic microRNAs (miRs), known to induce apoptosis by hybridizing with...

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Detalles Bibliográficos
Autores principales: Varma, Shambhu D., Kovtun, Svitlana, Hegde, Kavita, Yin, Jing, Ramnath, Jamuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380916/
https://www.ncbi.nlm.nih.gov/pubmed/22736950