Cargando…

Endothelial Cells Obtained from Patients Affected by Chronic Venous Disease Exhibit a Pro-Inflammatory Phenotype

BACKGROUND: The inflammatory properties of vein endothelium in relation to chronic venous disease (CVD) have been poorly investigated. Therefore, new insights on the characteristics of large vein endothelium would increase our knowledge of large vessel physiopathology. METHODOLOGY/PRINCIPAL FINDINGS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tisato, Veronica, Zauli, Giorgio, Voltan, Rebecca, Gianesini, Sergio, di Iasio, Maria Grazia, Volpi, Ilaria, Fiorentini, Guido, Zamboni, Paolo, Secchiero, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3380919/ https://www.ncbi.nlm.nih.gov/pubmed/22737245 http://dx.doi.org/10.1371/journal.pone.0039543

Ejemplares similares

GM-CSF Exhibits Anti-Inflammatory Activity on Endothelial Cells Derived from Chronic Venous Disease Patients
por: Tisato, Veronica, et al.
Publicado: (2013)

Inhibitory Effect of Natural Anti-Inflammatory Compounds on Cytokines Released by Chronic Venous Disease Patient-Derived Endothelial Cells
por: Tisato, Veronica, et al.
Publicado: (2013)

Modulation of Circulating Cytokine-Chemokine Profile in Patients Affected by Chronic Venous Insufficiency Undergoing Surgical Hemodynamic Correction
por: Tisato, Veronica, et al.
Publicado: (2014)

Clinical perspectives of TRAIL: insights into central nervous system disorders
por: Tisato, Veronica, et al.
Publicado: (2016)

MDM2/X inhibitors under clinical evaluation: perspectives for the management of hematological malignancies and pediatric cancer
por: Tisato, Veronica, et al.
Publicado: (2017)

In Vitro Endothelial Cell Proliferation Assay Reveals Distinct Levels of Proangiogenic Cytokines Characterizing Sera of Healthy Subjects and of Patients with Heart Failure
por: Voltan, Rebecca, et al.
Publicado: (2014)

HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts
por: Trapella, Claudio, et al.
Publicado: (2018)

Author Correction: HelixComplex snail mucus exhibits pro-survival, proliferative and pro-migration effects on mammalian fibroblasts
por: Trapella, Claudio, et al.
Publicado: (2020)

The calendar of cytokines: Seasonal variation of circulating cytokines in chronic venous insufficiency
por: Spath, Paolo, et al.
Publicado: (2017)

Rationale for Considering Oral Idasanutlin as a Therapeutic Option for COVID-19 Patients
por: Zauli, Giorgio, et al.
Publicado: (2020)

Lipids at the Nexus between Cerebrovascular Disease and Vascular Dementia: The Impact of HDL-Cholesterol and Ceramides
por: Sergi, Domenico, et al.
Publicado: (2023)

The γ-secretase inhibitors enhance the anti-leukemic activity of ibrutinib in B-CLL cells
por: Secchiero, Paola, et al.
Publicado: (2017)

Treatment With Recombinant Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Alleviates the Severity of Streptozotocin-Induced Diabetes
por: Zauli, Giorgio, et al.
Publicado: (2010)

Intranasal Administration of Recombinant TRAIL Down-Regulates CXCL-1/KC in an Ovalbumin-Induced Airway Inflammation Murine Model
por: Tisato, Veronica, et al.
Publicado: (2014)

TRAIL, OPG, and TWEAK in kidney disease: biomarkers or therapeutic targets?
por: Bernardi, Stella, et al.
Publicado: (2019)

Overcoming of Microenvironment Protection on Primary Chronic Lymphocytic Leukemia Cells after Treatment with BTK and MDM2 Pharmacological Inhibitors
por: Rimondi, Erika, et al.
Publicado: (2021)

Ultrastructure of internal jugular vein defective valves
por: Zamboni, P, et al.
Publicado: (2015)

Serum TRAIL levels increase shortly after insulin therapy and metabolic stabilization in children with type 1 diabetes mellitus
por: Tornese, Gianluca, et al.
Publicado: (2015)

COVID-19 and Individual Genetic Susceptibility/Receptivity: Role of ACE1/ACE2 Genes, Immunity, Inflammation and Coagulation. Might the Double X-Chromosome in Females Be Protective against SARS-CoV-2 Compared to the Single X-Chromosome in Males?
por: Gemmati, Donato, et al.
Publicado: (2020)

Low Circulating TRAIL Levels Are Associated with Increase of Resistin and Lipocalin-2/ngal Adipokines in Postmenopausal Women
por: Tisato, Veronica, et al.
Publicado: (2017)

TRAIL/DR5 pathway promotes AKT phosphorylation, skeletal muscle differentiation, and glucose uptake
por: Toffoli, Barbara, et al.
Publicado: (2021)

p53/NF-kB Balance in SARS-CoV-2 Infection: From OMICs, Genomics and Pharmacogenomics Insights to Tailored Therapeutic Perspectives (COVIDomics)
por: Milani, Daniela, et al.
Publicado: (2022)

Sex/Gender-Specific Imbalance in CVD: Could Physical Activity Help to Improve Clinical Outcome Targeting CVD Molecular Mechanisms in Women?
por: Vaccarezza, Mauro, et al.
Publicado: (2020)

Therapeutic potential of the MDM2 inhibitor Nutlin-3 in counteracting SARS-CoV-2 infection of the eye through p53 activation
por: Zauli, Giorgio, et al.
Publicado: (2022)

Kinetic Profiles of Inflammatory Mediators in the Conjunctival Sac Fluid of Patients upon Photorefractive Keratectomy
por: Tisato, Veronica, et al.
Publicado: (2015)

Relationship between low levels of circulating TRAIL and atheromatosis progression in patients with chronic kidney disease
por: Arcidiacono, Maria Vittoria, et al.
Publicado: (2018)

miRNAs Epigenetic Tuning of Wall Remodeling in the Early Phase after Myocardial Infarction: A Novel Epidrug Approach
por: Salvatori, Francesca, et al.
Publicado: (2023)

Surgical Technique for Deep Venous Reflux Suppression in Femoral Vein Duplication
por: Zamboni, P., et al.
Publicado: (2016)

Metformin combined with sodium dichloroacetate promotes B leukemic cell death by suppressing anti-apoptotic protein Mcl-1
por: Voltan, Rebecca, et al.
Publicado: (2016)

Maternal Haplotypes in DHFR Promoter and MTHFR Gene in Tuning Childhood Acute Lymphoblastic Leukemia Onset-Latency: Genetic/Epigenetic Mother/Child Dyad Study (GEMCDS)
por: Tisato, Veronica, et al.
Publicado: (2019)

Cell cycle block by p53 activation reduces SARS-CoV-2 release in infected alveolar basal epithelial A549-hACE2 cells
por: Lodi, Giada, et al.
Publicado: (2022)

Soluble TRAIL does not impair the anti-osteoclastic activity of osteoprotegerin
por: Zauli, Giorgio, et al.
Publicado: (2008)

In Vitro Characterization of Circulating Endothelial Progenitor Cells Isolated from Patients with Acute Coronary Syndrome
por: Campioni, Diana, et al.
Publicado: (2013)

Inflammation and Cardiovascular Cross Talk in Ischemic Vascular Diseases
por: Zauli, Giorgio, et al.
Publicado: (2017)

TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
por: Tisato, Veronica, et al.
Publicado: (2018)

Ibrutinib synergizes with MDM-2 inhibitors in promoting cytotoxicity in B chronic lymphocytic leukemia
por: Voltan, Rebecca, et al.
Publicado: (2016)

Cell-Based Therapies for Diabetic Complications
por: Bernardi, Stella, et al.
Publicado: (2012)

Palmitic Acid Induced a Long-Lasting Lipotoxic Insult in Human Retinal Pigment Epithelial Cells, which Is Partially Counteracted by TRAIL
por: Sergi, Domenico, et al.
Publicado: (2022)

Host genetics impact on SARS-CoV-2 vaccine-induced immunoglobulin levels and dynamics: The role of TP53, ABO, APOE, ACE2, HLA-A, and CRP genes
por: Gemmati, Donato, et al.
Publicado: (2022)

Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3
por: Agnoletto, Chiara, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_fomnclq4emn5rdvrgshkp9hr0n