Intravitreal Bevacizumab for Choroidal Metastasis of Lung Carcinoma; a Case Report

PURPOSE: To report an alternative treatment for metastatic tumors within the eye. CASE REPORT: Five intravitreal injections of bevacizumab (2.5 mg each) were performed in one eye of a 50-year-old woman with choroidal metastasis of lung carcinoma. Tumor size was reduced, pain disappeared, vision impr...

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Detalles Bibliográficos
Autores principales: de la Barquera Cordero, Aída Sánchez, Hidalgo, Rene Alfredo Cano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ophthalmic Research Center 2010
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381081/
https://www.ncbi.nlm.nih.gov/pubmed/22737371
Descripción
Sumario:PURPOSE: To report an alternative treatment for metastatic tumors within the eye. CASE REPORT: Five intravitreal injections of bevacizumab (2.5 mg each) were performed in one eye of a 50-year-old woman with choroidal metastasis of lung carcinoma. Tumor size was reduced, pain disappeared, vision improved, and there were no secondary reactions. Vision improved from 20/40 to 20/20 and metamorphopsia decreased. Ten months after initiating treatment, an ultrasonographic study revealed no residual tumor, the choroid was normal in thickness and fluorescein angiography revealed a scar but no mass lesion. CONCLUSION: Intravitreal bevacizumab displayed beneficial effects in reducing tumor size and improving symptoms in this case of choroidal metastasis of lung carcinoma. The antineoplasic properties of this agent make it a viable alternative for treatment of metastatic choroidal tumors.

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