Regenerative Therapy for Retinal Disorders

Major advances in various disciplines of basic sciences including embryology, molecular and cell biology, genetics, and nanotechnology, as well as stem cell biology have opened new horizons for regenerative therapy. The unique characteristics of stem cells prompt a sound understanding for their use...

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Detalles Bibliográficos
Autores principales: Daftarian, Narsis, Kiani, Sahar, Zahabi, Azadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ophthalmic Research Center 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381091/
https://www.ncbi.nlm.nih.gov/pubmed/22737370
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author Daftarian, Narsis
Kiani, Sahar
Zahabi, Azadeh
author_facet Daftarian, Narsis
Kiani, Sahar
Zahabi, Azadeh
author_sort Daftarian, Narsis
collection PubMed
description Major advances in various disciplines of basic sciences including embryology, molecular and cell biology, genetics, and nanotechnology, as well as stem cell biology have opened new horizons for regenerative therapy. The unique characteristics of stem cells prompt a sound understanding for their use in modern regenerative therapies. This review article discusses stem cells, developmental stages of the eye field, eye field transcriptional factors, and endogenous and exogenous sources of stem cells. Recent studies and challenges in the application of stem cells for retinal pigment epithelial degeneration models will be summarized followed by obstacles facing regenerative therapy.
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spelling pubmed-33810912012-06-26 Regenerative Therapy for Retinal Disorders Daftarian, Narsis Kiani, Sahar Zahabi, Azadeh J Ophthalmic Vis Res Review Article Major advances in various disciplines of basic sciences including embryology, molecular and cell biology, genetics, and nanotechnology, as well as stem cell biology have opened new horizons for regenerative therapy. The unique characteristics of stem cells prompt a sound understanding for their use in modern regenerative therapies. This review article discusses stem cells, developmental stages of the eye field, eye field transcriptional factors, and endogenous and exogenous sources of stem cells. Recent studies and challenges in the application of stem cells for retinal pigment epithelial degeneration models will be summarized followed by obstacles facing regenerative therapy. Ophthalmic Research Center 2010-10 /pmc/articles/PMC3381091/ /pubmed/22737370 Text en http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Daftarian, Narsis
Kiani, Sahar
Zahabi, Azadeh
Regenerative Therapy for Retinal Disorders
title Regenerative Therapy for Retinal Disorders
title_full Regenerative Therapy for Retinal Disorders
title_fullStr Regenerative Therapy for Retinal Disorders
title_full_unstemmed Regenerative Therapy for Retinal Disorders
title_short Regenerative Therapy for Retinal Disorders
title_sort regenerative therapy for retinal disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381091/
https://www.ncbi.nlm.nih.gov/pubmed/22737370
work_keys_str_mv AT daftariannarsis regenerativetherapyforretinaldisorders
AT kianisahar regenerativetherapyforretinaldisorders
AT zahabiazadeh regenerativetherapyforretinaldisorders

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