A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection

Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and ce...

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Autores principales: Sim, Jae Eun, Lee, Jun-Bum, Cho, Yu Na, Suh, Sang Hyun, Kim, Ja Kyung, Lee, Kyung-Yul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2012
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381478/
https://www.ncbi.nlm.nih.gov/pubmed/22665357
http://dx.doi.org/10.3349/ymj.2012.53.4.856
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author Sim, Jae Eun
Lee, Jun-Bum
Cho, Yu Na
Suh, Sang Hyun
Kim, Ja Kyung
Lee, Kyung-Yul
author_facet Sim, Jae Eun
Lee, Jun-Bum
Cho, Yu Na
Suh, Sang Hyun
Kim, Ja Kyung
Lee, Kyung-Yul
author_sort Sim, Jae Eun
collection PubMed
description Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and cerebrospinal fluid (CSF) anti-HCV antibody. After steroid treatment, neurologic symptoms were improved. Virus triggers autoimmunity or direct viral invasion plays a part in the genesis of ADEM. This is the first reported case of ADEM with anti-HCV antibody in the CSF.
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spelling pubmed-33814782012-07-01 A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection Sim, Jae Eun Lee, Jun-Bum Cho, Yu Na Suh, Sang Hyun Kim, Ja Kyung Lee, Kyung-Yul Yonsei Med J Case Report Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and cerebrospinal fluid (CSF) anti-HCV antibody. After steroid treatment, neurologic symptoms were improved. Virus triggers autoimmunity or direct viral invasion plays a part in the genesis of ADEM. This is the first reported case of ADEM with anti-HCV antibody in the CSF. Yonsei University College of Medicine 2012-07-01 2012-05-22 /pmc/articles/PMC3381478/ /pubmed/22665357 http://dx.doi.org/10.3349/ymj.2012.53.4.856 Text en © Copyright: Yonsei University College of Medicine 2012 http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Sim, Jae Eun
Lee, Jun-Bum
Cho, Yu Na
Suh, Sang Hyun
Kim, Ja Kyung
Lee, Kyung-Yul
A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title_full A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title_fullStr A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title_full_unstemmed A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title_short A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection
title_sort case of acute disseminated encephalomyelitis associated with hepatitis c virus infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381478/
https://www.ncbi.nlm.nih.gov/pubmed/22665357
http://dx.doi.org/10.3349/ymj.2012.53.4.856
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