Formulation of Small Activating RNA Into Lipidoid Nanoparticles Inhibits Xenograft Prostate Tumor Growth by Inducing p21 Expression

Application of RNA interference (RNAi) in the clinic has improved with the development of novel delivery reagents (e.g., lipidoids). Although RNAi promises a therapeutic approach at silencing gene expression, practical methods for enhancing gene production still remain a challenge. Previously, we re...

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Detalles Bibliográficos
Autores principales: Place, Robert F, Wang, Ji, Noonan, Emily J, Meyers, Rachel, Manoharan, Muthiah, Charisse, Klaus, Duncan, Rick, Huang, Vera, Wang, Xiaoling, Li, Long-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381590/
https://www.ncbi.nlm.nih.gov/pubmed/23343884
http://dx.doi.org/10.1038/mtna.2012.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381590/
https://www.ncbi.nlm.nih.gov/pubmed/23343884
http://dx.doi.org/10.1038/mtna.2012.5

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