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Yes and Lyn play a role in nuclear translocation of the Epidermal Growth Factor Receptor

The epidermal growth factor receptor (EGFR) is a central regulator of tumor progression in human cancers. Cetuximab is an anti-EGFR antibody that has been approved for use in oncology. Previously we investigated mechanisms of resistance to cetuximab using a model derived from the non-small cell lung...

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Detalles Bibliográficos
Autores principales: Iida, Mari, Brand, Toni M., Campbell, David A, Li, Chunrong, Wheeler, Deric L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381861/
https://www.ncbi.nlm.nih.gov/pubmed/22430206
http://dx.doi.org/10.1038/onc.2012.90