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Axonal transport of adeno-associated viral vectors is serotype-dependent

We have previously shown that AAV2 undergoes anterograde axonal transport in rat and non-human primate brain. We screened other AAV serotypes for axonal transport and found that AAV6 is transported almost exclusively in a retrograde direction and, like AAV2, it is also neuron-specific in rat brain....

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Detalles Bibliográficos
Autores principales:	Salegio, Ernesto A., Samaranch, Lluis, Kells, Adrian P., Mittermeyer, Gabriele, San Sebastian, Waldy, Zhou, Shangzhen, Beyer, Janine, Forsayeth, John, Bankiewicz, Krystof S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381869/ https://www.ncbi.nlm.nih.gov/pubmed/22418061 http://dx.doi.org/10.1038/gt.2012.27

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