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Chronic VEGF Blockade Worsens Glomerular Injury in the Remnant Kidney Model

VEGF inhibition can promote renal vascular and parenchymal injury, causing proteinuria, hypertension and thrombotic microangiopathy. The mechanisms underlying these side effects are unclear. We investigated the renal effects of the administration, during 45 days, of sunitinib (Su), a VEGF receptor i...

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Detalles Bibliográficos
Autores principales:	Machado, Flavia G., Kuriki, Patrícia Semedo, Fujihara, Clarice K., Fanelli, Camilla, Arias, Simone C. A., Malheiros, Denise M. A. C., Camara, Niels O. S., Zatz, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382123/ https://www.ncbi.nlm.nih.gov/pubmed/22745791 http://dx.doi.org/10.1371/journal.pone.0039580

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