Cargando…

Vascular Endothelial Growth Factor Receptor-3 Directly Interacts with Phosphatidylinositol 3-Kinase to Regulate Lymphangiogenesis

BACKGROUND: Dysfunctional lymphatic vessel formation has been implicated in a number of pathological conditions including cancer metastasis, lymphedema, and impaired wound healing. The vascular endothelial growth factor (VEGF) family is a major regulator of lymphatic endothelial cell (LEC) function...

Descripción completa

Detalles Bibliográficos
Autores principales: Coso, Sanja, Zeng, Yiping, Opeskin, Kenneth, Williams, Elizabeth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382126/
https://www.ncbi.nlm.nih.gov/pubmed/22745786
http://dx.doi.org/10.1371/journal.pone.0039558