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Sec5 and Exo84 Mediate Distinct Aspects of RalA-Dependent Cell Polarization

Metastasis is a complex process during which several gross cellular changes occur. Cells must dissociate from the tumor mass and gain the ability to degrade extracellular matrix and migrate in order to ultimately attach and form a satellite tumor. Regulation of the actin cytoskeleton is an indispens...

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Detalles Bibliográficos
Autores principales: Hazelett, C. Clayton, Yeaman, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382198/
https://www.ncbi.nlm.nih.gov/pubmed/22761837
http://dx.doi.org/10.1371/journal.pone.0039602