Cargando…
Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies
Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Usin...
Autores principales: | Frazer, J. Kimble, Batchelor, Lance A., Bradley, Diana F., Brown, Kim H., Dobrinski, Kimberly P., Lee, Charles, Trede, Nikolaus S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382231/ https://www.ncbi.nlm.nih.gov/pubmed/22745640 http://dx.doi.org/10.1155/2012/627920 |
Ejemplares similares
-
Heritable T Cell Malignancy Models Established in a Zebrafish Phenotypic Screen
por: Frazer, J. Kimble, et al.
Publicado: (2009) -
Endogenous retroviruses of the chicken genome
por: Huda, Ahsan, et al.
Publicado: (2008) -
Endogenous retroviruses in primates
por: Brown, Katherine, et al.
Publicado: (2011) -
Endogenous retroviruses in the human genome sequence
por: Griffiths, David J
Publicado: (2001) -
A model 450 million years in the making: zebrafish and vertebrate immunity
por: Renshaw, Stephen A., et al.
Publicado: (2012)