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Genomic Amplification of an Endogenous Retrovirus in Zebrafish T-Cell Malignancies

Genomic instability plays a crucial role in oncogenesis. Somatically acquired mutations can disable some genes and inappropriately activate others. In addition, chromosomal rearrangements can amplify, delete, or even fuse genes, altering their functions and contributing to malignant phenotypes. Usin...

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Detalles Bibliográficos
Autores principales: Frazer, J. Kimble, Batchelor, Lance A., Bradley, Diana F., Brown, Kim H., Dobrinski, Kimberly P., Lee, Charles, Trede, Nikolaus S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382231/
https://www.ncbi.nlm.nih.gov/pubmed/22745640
http://dx.doi.org/10.1155/2012/627920

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