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BAY 11-7082 Is a Broad-Spectrum Inhibitor with Anti-Inflammatory Activity against Multiple Targets

BAY 11-7082 (BAY) is an inhibitor of κB kinase (IKK) that has pharmacological activities that include anticancer, neuroprotective, and anti-inflammatory effects. In this study, BAY-pharmacological target pathways were further characterized to determine how this compound simultaneously suppresses var...

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Detalles Bibliográficos
Autores principales: Lee, Jaehwi, Rhee, Man Hee, Kim, Eunji, Cho, Jae Youl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382285/
https://www.ncbi.nlm.nih.gov/pubmed/22745523
http://dx.doi.org/10.1155/2012/416036