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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target
Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...
Autores principales: | Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382371/ https://www.ncbi.nlm.nih.gov/pubmed/22571657 http://dx.doi.org/10.2174/138161212800672750 |
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