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Perspective of Cyclin-dependent kinase 9 (CDK9) as a Drug Target

Deregulation of cyclin-dependent kinases (CDKs) has been associated with many cancer types and has evoked an interest in chemical inhibitors with possible therapeutic benefit. While most known inhibitors display broad selectivity towards multiple CDKs, recent work highlights CDK9 as the critical tar...

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Detalles Bibliográficos
Autores principales: Kryštof, Vladimír, Baumli, Sonja, Fürst, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382371/
https://www.ncbi.nlm.nih.gov/pubmed/22571657
http://dx.doi.org/10.2174/138161212800672750

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