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HEMD: An Integrated Tool of Human Epigenetic Enzymes and Chemical Modulators for Therapeutics

BACKGROUND: Epigenetic mechanisms mainly include DNA methylation, post-translational modifications of histones, chromatin remodeling and non-coding RNAs. All of these processes are mediated and controlled by enzymes. Abnormalities of the enzymes are involved in a variety of complex human diseases. R...

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Detalles Bibliográficos
Autores principales: Huang, Zhimin, Jiang, Haiming, Liu, Xinyi, Chen, Yingyi, Wong, Jiemin, Wang, Qi, Huang, Wenkang, Shi, Ting, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382562/
https://www.ncbi.nlm.nih.gov/pubmed/22761927
http://dx.doi.org/10.1371/journal.pone.0039917