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HEMD: An Integrated Tool of Human Epigenetic Enzymes and Chemical Modulators for Therapeutics
BACKGROUND: Epigenetic mechanisms mainly include DNA methylation, post-translational modifications of histones, chromatin remodeling and non-coding RNAs. All of these processes are mediated and controlled by enzymes. Abnormalities of the enzymes are involved in a variety of complex human diseases. R...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382562/ https://www.ncbi.nlm.nih.gov/pubmed/22761927 http://dx.doi.org/10.1371/journal.pone.0039917 |