Regulation of a Truncated Form of Tropomyosin-Related Kinase B (TrkB) by Hsa-miR-185* in Frontal Cortex of Suicide Completers

BACKGROUND: TrkB-T1 is a BDNF receptor lacking a tyrosine kinase domain that is highly expressed in astrocytes and regulates BDNF-evoked calcium transients. Previous studies indicate that downregulation of TrkB-T1 in frontal cortex may be involved in neurobiological processes underlying suicide. MET...

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Detalles Bibliográficos
Autores principales: Maussion, Gilles, Yang, Jennie, Yerko, Volodymyr, Barker, Philip, Mechawar, Naguib, Ernst, Carl, Turecki, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382618/
https://www.ncbi.nlm.nih.gov/pubmed/22802923
http://dx.doi.org/10.1371/journal.pone.0039301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382618/
https://www.ncbi.nlm.nih.gov/pubmed/22802923
http://dx.doi.org/10.1371/journal.pone.0039301

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