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Investigation of Antigen-Antibody Interactions of Sulfonamides with a Monoclonal Antibody in a Fluorescence Polarization Immunoassay Using 3D-QSAR Models

A three-dimensional quantitative structure-activity relationship (3D-QSAR) model of sulfonamide analogs binding a monoclonal antibody (MAb(SMR)) produced against sulfamerazine was carried out by Distance Comparison (DISCOtech), comparative molecular field analysis (CoMFA), and comparative molecular...

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Detalles Bibliográficos
Autores principales: Wang, Zhanhui, Kai, Zhenpeng, Beier, Ross C., Shen, Jianzhong, Yang, Xinling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382755/
https://www.ncbi.nlm.nih.gov/pubmed/22754368
http://dx.doi.org/10.3390/ijms13056334