Cargando…

Characterization of ARF-BP1/HUWE1 Interactions with CTCF, MYC, ARF and p53 in MYC-Driven B Cell Neoplasms

Transcriptional activation of MYC is a hallmark of many B cell lineage neoplasms. MYC provides a constitutive proliferative signal but can also initiate ARF-dependent activation of p53 and apoptosis. The E3 ubiquitin ligase, ARF-BP1, encoded by HUWE1, modulates the activity of both the MYC and the A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qi, Chen-Feng, Kim, Yong-Soo, Xiang, Shao, Abdullaev, Ziedulla, Torrey, Ted A., Janz, Siegfried, Kovalchuk, Alexander L., Sun, Jiafang, Chen, Delin, Cho, William C., Gu, Wei, Morse, Herbert C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382761/ https://www.ncbi.nlm.nih.gov/pubmed/22754359 http://dx.doi.org/10.3390/ijms13056204

Ejemplares similares

ARF-BP1 as a potential therapeutic target
por: Chen, D, et al.
Publicado: (2006)

Tipping the MYC–MIZ1 balance: targeting the HUWE1 ubiquitin ligase selectively blocks MYC-activated genes
por: Schaub, Franz X, et al.
Publicado: (2014)

ARF suppression by MYC but not MYCN confers increased malignancy of aggressive pediatric brain tumors
por: Mainwaring, Oliver J., et al.
Publicado: (2023)

EMBR-07. MYC BUT NOT MYCN GENERATES AGGRESSIVE GROUP 3 MEDULLOBLASTOMA BY ARF PATHWAY SUPPRESSION
por: Mainwaring, Oliver, et al.
Publicado: (2021)

KRAS, MYC, and ARF6: inseparable relationships cooperatively promote cancer malignancy and immune evasion
por: Sabe, Hisataka
Publicado: (2023)

Differential roles of ArfGAP1, ArfGAP2, and ArfGAP3 in COPI trafficking
por: Weimer, Carolin, et al.
Publicado: (2008)

The E3 ligase HUWE1 inhibition as a therapeutic strategy to target MYC in multiple myeloma
por: Crawford, Lisa J., et al.
Publicado: (2020)

Targeted Deletion of Multiple CTCF-Binding Elements in the Human C-MYC Gene Reveals a Requirement for CTCF in C-MYC Expression
por: Gombert, Wendy M., et al.
Publicado: (2009)

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway
por: Nagao, Motoshi, et al.
Publicado: (2008)

Coordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19(ARF)–p53 pathway
por: Nagao, Motoshi, et al.
Publicado: (2009)

MYC activation cooperates with Vhl and Ink4a/Arf loss to induce clear cell renal cell carcinoma
por: Bailey, Sean T., et al.
Publicado: (2017)

MYC reshapes CTCF-mediated chromatin architecture in prostate cancer
por: Wei, Zhao, et al.
Publicado: (2023)

Tumor cell-specific inhibition of MYC function using small molecule inhibitors of the HUWE1 ubiquitin ligase
por: Peter, Stefanie, et al.
Publicado: (2014)

ARAP1 regulates the ring size of circular dorsal ruffles through Arf1 and Arf5
por: Hasegawa, Junya, et al.
Publicado: (2012)

The Arf GAP Asap promotes Arf1 function at the Golgi for cleavage furrow biosynthesis in Drosophila
por: Rodrigues, Francisco F., et al.
Publicado: (2016)

The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi
por: Meissner, Justyna M., et al.
Publicado: (2023)

Ink4a and Arf are crucial factors in the determination of the cell of origin and the therapeutic sensitivity of Myc-induced mouse lymphoid tumor
por: Sugihara, Eiji, et al.
Publicado: (2011)

Myr-Arf1 conformational flexibility at the membrane surface sheds light on the interactions with ArfGAP ASAP1
por: Zhang, Yue, et al.
Publicado: (2023)

Overexpression of wild-type and mutant ARF1 and ARF6: distinct perturbations of nonoverlapping membrane compartments
Publicado: (1995)

Characterization of cotton ARF factors and the role of GhARF2b in fiber development
por: Zhang, Xiufang, et al.
Publicado: (2021)

ARF1 and ARF4 regulate recycling endosomal morphology and retrograde transport from endosomes to the Golgi apparatus
por: Nakai, Waka, et al.
Publicado: (2013)

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation
por: Myant, Kevin B, et al.
Publicado: (2016)

The Arf GEF GBF1 integrates inputs from its product, Arf4·GTP, and the Golgi influx of sensory membrane cargo to activate Arf4 in ciliary trafficking
por: Deretic, D, et al.
Publicado: (2015)

Arf1 doubles up to release vesicles
por: Short, Ben
Publicado: (2011)

ARF1 at the crossroads of podosome construction and function
por: Genot, Elisabeth
Publicado: (2017)

The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression
por: Yuan, Ye, et al.
Publicado: (2022)

Tobacco TTG2 regulates vegetative growth and seed production via the predominant role of ARF8 in cooperation with ARF17 and ARF19
por: Ge, Jun, et al.
Publicado: (2016)

Hazara Nairovirus Requires COPI Components in both Arf1-Dependent and Arf1-Independent Stages of Its Replication Cycle
por: Fuller, J., et al.
Publicado: (2020)

Nomenclature for the human Arf family of GTP-binding proteins: ARF, ARL, and SAR proteins
por: Kahn, Richard A., et al.
Publicado: (2006)

Bayesian classification of residues associated with protein functional divergence: Arf and Arf-like GTPases
por: Neuwald, Andrew F
Publicado: (2010)

Effect of RAD51C expression on the chemosensitivity of Eμ-Myc p19(Arf−/−) cells and its clinical significance in breast cancer
por: Liao, Shao-Guang, et al.
Publicado: (2018)

Genome-wide identification of the GhARF gene family reveals that GhARF2 and GhARF18 are involved in cotton fibre cell initiation
por: Xiao, Guanghui, et al.
Publicado: (2018)

The leukemic oncogene EVI1 hijacks a MYC super-enhancer by CTCF-facilitated loops
por: Ottema, Sophie, et al.
Publicado: (2021)

Inhibition of mutant KRAS-driven overexpression of ARF6 and MYC by an eIF4A inhibitor drug improves the effects of anti-PD-1 immunotherapy for pancreatic cancer
por: Hashimoto, Ari, et al.
Publicado: (2021)

Nucleostemin: New Stabilizer of ARF
por: Cao, Bo, et al.
Publicado: (2015)

ARF-Like (ARL) Proteins
por: Kahn, Richard A., et al.
Publicado: (2014)

Expression of the CTCF-paralogous cancer-testis gene, brother of the regulator of imprinted sites (BORIS), is regulated by three alternative promoters modulated by CpG methylation and by CTCF and p53 transcription factors
por: Renaud, Stéphanie, et al.
Publicado: (2007)

Auxin Response Factor 2 (ARF2), ARF3, and ARF4 Mediate Both Lateral Root and Nitrogen Fixing Nodule Development in Medicago truncatula
por: Kirolinko, Cristina, et al.
Publicado: (2021)

p19ARF is a critical mediator of both cellular senescence and an innate immune response associated with MYC inactivation in mouse model of acute leukemia
por: Yetil, Alper, et al.
Publicado: (2015)

Arf and Miz1 cause cells to lose their grip
por: Short, Ben
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_5lqt9mcbqaph6dvb0tbs27dub3