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The Quiescent Cellular State is Arf/p53-Dependent and Associated with H2AX Downregulation and Genome Stability

Cancer is a disease associated with genomic instability and mutations. Excluding some tumors with specific chromosomal translocations, most cancers that develop at an advanced age are characterized by either chromosomal or microsatellite instability. However, it is still unclear how genomic instabil...

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Detalles Bibliográficos
Autores principales: Yoshioka, Ken-ichi, Atsumi, Yuko, Fukuda, Hirokazu, Masutani, Mitsuko, Teraoka, Hirobumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382772/
https://www.ncbi.nlm.nih.gov/pubmed/22754379
http://dx.doi.org/10.3390/ijms13056492