Design and Characterization of a Peptide Mimotope of the HIV-1 gp120 Bridging Sheet

The Bridging Sheet domain of HIV-1 gp120 is highly conserved among the HIV-1 strains and allows HIV-1 binding to host cells via the HIV-1 coreceptors. Further, the bridging sheet domain is a major target to neutralize HIV-1 infection. We rationally designed four linear peptide epitopes that mimic th...

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Detalles Bibliográficos
Autores principales: Schiavone, Marco, Fiume, Giuseppe, Caivano, Antonella, de Laurentiis, Annamaria, Falcone, Cristina, Masci, Francesca Fasanella, Iaccino, Enrico, Mimmi, Selena, Palmieri, Camillo, Pisano, Antonio, Pontoriero, Marilena, Rossi, Annalisa, Scialdone, Annarita, Vecchio, Eleonora, Andreozzi, Concetta, Trovato, Maria, Rafay, Jan, Ferko, Boris, Montefiori, David, Lombardi, Angela, Morsica, Giulia, Poli, Guido, Quinto, Ileana, Pavone, Vincenzo, de Berardinis, Piergiuseppe, Scala, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382813/
https://www.ncbi.nlm.nih.gov/pubmed/22754323
http://dx.doi.org/10.3390/ijms13055674

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