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Egfl7 promotes tumor escape from immunity
Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by downregulating the expression of leukocyte adhesion molecules in endothelial cells, thus repressing immune cell extravasation into tumors.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382845/ https://www.ncbi.nlm.nih.gov/pubmed/22737620 http://dx.doi.org/10.4161/onci.18964 |
| _version_ | 1782236558241300480 |
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| author | Pinte, Sébastien Soncin, Fabrice |
| author_facet | Pinte, Sébastien Soncin, Fabrice |
| author_sort | Pinte, Sébastien |
| collection | PubMed |
| description | Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by downregulating the expression of leukocyte adhesion molecules in endothelial cells, thus repressing immune cell extravasation into tumors. |
| format | Online Article Text |
| id | pubmed-3382845 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33828452012-06-26 Egfl7 promotes tumor escape from immunity Pinte, Sébastien Soncin, Fabrice Oncoimmunology Author's View Egfl7 is an endothelial-specific gene which expression is deregulated in human cancers. We showed that Egfl7 promotes tumor escape from immunity by downregulating the expression of leukocyte adhesion molecules in endothelial cells, thus repressing immune cell extravasation into tumors. Landes Bioscience 2012-05-01 /pmc/articles/PMC3382845/ /pubmed/22737620 http://dx.doi.org/10.4161/onci.18964 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Pinte, Sébastien Soncin, Fabrice Egfl7 promotes tumor escape from immunity |
| title | Egfl7 promotes tumor escape from immunity |
| title_full | Egfl7 promotes tumor escape from immunity |
| title_fullStr | Egfl7 promotes tumor escape from immunity |
| title_full_unstemmed | Egfl7 promotes tumor escape from immunity |
| title_short | Egfl7 promotes tumor escape from immunity |
| title_sort | egfl7 promotes tumor escape from immunity |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382845/ https://www.ncbi.nlm.nih.gov/pubmed/22737620 http://dx.doi.org/10.4161/onci.18964 |
| work_keys_str_mv | AT pintesebastien egfl7promotestumorescapefromimmunity AT soncinfabrice egfl7promotestumorescapefromimmunity |