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Activation of PPARγ in myeloid cells promotes lung cancer progression and metastasis

PPARγ activators inhibit cancer cell growth. However the role of these agents in progression/metastasis is not well-defined. Using an orthotopic model of lung cancer, we showed that pioglitazone accelerated progression/metastasis through affects on macrophages. This suggests that potential therapeut...

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Detalles Bibliográficos
Autor principal: Nemenoff, Raphael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382846/
https://www.ncbi.nlm.nih.gov/pubmed/22737631
http://dx.doi.org/10.4161/onci.19309

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