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Under one roof: The bone marrow survival niche for multiple myeloma and normal plasma cells

Our recently published data demonstrate significant similarities between normal and malignant plasma cells in the cellular and molecular interactions that support their survival in the bone marrow microenvironment, and suggest that the biology of multiple myeloma may largely reflect that of their no...

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Detalles Bibliográficos
Autores principales: Nair, Jayakumar R., Rozanski, Cheryl H., Lee, Kelvin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382851/
https://www.ncbi.nlm.nih.gov/pubmed/22737625
http://dx.doi.org/10.4161/onci.18746
Descripción
Sumario:Our recently published data demonstrate significant similarities between normal and malignant plasma cells in the cellular and molecular interactions that support their survival in the bone marrow microenvironment, and suggest that the biology of multiple myeloma may largely reflect that of their normal counterparts.