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How to develop better screens for anti-cancer therapies?
The clinical efficacy of chemotherapy relies in part on its ability to potentiate anti-tumor immune responses. Recent work shows that several chemotherapeutic drugs induce intra-tumoral expression of lymphocyte-attracting chemokines, leading to clinical responses. Here, we argue that such knowledge...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382852/ https://www.ncbi.nlm.nih.gov/pubmed/22737623 http://dx.doi.org/10.4161/onci.18805 |
| _version_ | 1782236559807873024 |
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| author | Hong, Michelle Abastado, Jean-Pierre |
| author_facet | Hong, Michelle Abastado, Jean-Pierre |
| author_sort | Hong, Michelle |
| collection | PubMed |
| description | The clinical efficacy of chemotherapy relies in part on its ability to potentiate anti-tumor immune responses. Recent work shows that several chemotherapeutic drugs induce intra-tumoral expression of lymphocyte-attracting chemokines, leading to clinical responses. Here, we argue that such knowledge should be used to screen for novel anti-tumor treatments. |
| format | Online Article Text |
| id | pubmed-3382852 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Landes Bioscience |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-33828522012-06-26 How to develop better screens for anti-cancer therapies? Hong, Michelle Abastado, Jean-Pierre Oncoimmunology Author's View The clinical efficacy of chemotherapy relies in part on its ability to potentiate anti-tumor immune responses. Recent work shows that several chemotherapeutic drugs induce intra-tumoral expression of lymphocyte-attracting chemokines, leading to clinical responses. Here, we argue that such knowledge should be used to screen for novel anti-tumor treatments. Landes Bioscience 2012-05-01 /pmc/articles/PMC3382852/ /pubmed/22737623 http://dx.doi.org/10.4161/onci.18805 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| spellingShingle | Author's View Hong, Michelle Abastado, Jean-Pierre How to develop better screens for anti-cancer therapies? |
| title | How to develop better screens for anti-cancer therapies? |
| title_full | How to develop better screens for anti-cancer therapies? |
| title_fullStr | How to develop better screens for anti-cancer therapies? |
| title_full_unstemmed | How to develop better screens for anti-cancer therapies? |
| title_short | How to develop better screens for anti-cancer therapies? |
| title_sort | how to develop better screens for anti-cancer therapies? |
| topic | Author's View |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382852/ https://www.ncbi.nlm.nih.gov/pubmed/22737623 http://dx.doi.org/10.4161/onci.18805 |
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