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Human dendritic cells adenovirally-engineered to express three defined tumor antigens promote broad adaptive and innate immunity
Dendritic cell (DC) immunotherapy has shown a promising ability to promote anti-tumor immunity in vitro and in vivo. Many trials have tested single epitopes and single antigens to activate single T cell specificities, and often CD8(+) T cells only. We previously found that determinant spreading and...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382861/ https://www.ncbi.nlm.nih.gov/pubmed/22737604 http://dx.doi.org/10.4161/onci.18628 |