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The combination of histone deacetylase inhibitors with immune-stimulating antibodies has potent anti-cancer effects

The use of immunotherapy to treat cancer is rapidly gaining momentum. Using pre-clinical mouse models, we have recently demonstrated potent and long lasting tumor regression can be elicited by immune-stimulating monoclonal antibodies (mAbs) when combined with histone deacetylase inhibitors (HDACi) a...

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Detalles Bibliográficos
Autores principales:	West, Alison C., Christiansen, Ailsa J., Smyth, Mark J., Johnstone, Ricky W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382866/ https://www.ncbi.nlm.nih.gov/pubmed/22737621 http://dx.doi.org/10.4161/onci.18804

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